Werkgroep Statistiek en Micro-Arrays, ter gelegenheid van de 15de verjaardag van het Centre for Biostatistics, Utrecht “The role of Biostatistics in Bioinformatics”

Program

10:00	Opening
10:05 ÷ 10:25	Design of micro-array experiments: common reference vs.(extended) loop designs  Cas Kruitwagen (UU)
10:25 ÷ 10:45	Statistical Quality Assurance in Mass Spectrometry for Proteomics Paul Eilers (LUMC)
10:45 ÷ 11:00	Estimating the False Discovery Rate for interval null-hypotheses Mark van de Wiel (TUE)
11:00 ÷ 11:30	Coffee break
11:30 ÷ 11:50	The Global Test: Testing association of genetic pathways with survival of patients using microarray data Jelle Goeman (LUMC)
11:50 ÷ 12:10	Generalizable contrasts in expression microarrays Estimation of missing data and haplotypes without using E-M estimation in whole genome association studies Gerard te Meerman (UMCG)
12:10 ÷ 12:30	Discussion
12:30 ÷ 13:30	Lunch
13:30 ÷ 14:10	Statistomics (or why statistics is vital to genomics) Ritsert Jansen (Groningen Bioinformatics Centre, University of Groningen)
14:10 ÷ 14:40	Meta-analysis for linkage genome scans: an example from the GenomEUtwin project Hein Putter (Medical Statistics, Leiden University Medical Centre)
14:40 ÷ 15:00	Tea Break
15:00 ÷ 15:30	Sequential analysis of genetic studies Ingeborg van der Tweel & Maria Schipper (Centre for Biostatistics, Utrecht University)
15:30	Special session on gene expression profiling in breast cancer
15:30 ÷ 16:00	The Amsterdam experience Guus Hart (Netherlands Cancer Institute)
16:00 ÷ 16:30	The Rotterdam experience John Foekens (Laboratory of Tumor Endocrinology, Erasmus Medical Centre)